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The gabapentinoid drugs and their abuse potential
Pharmacology & Therapeutics ( IF 12.0 ) Pub Date : 2021-06-22 , DOI: 10.1016/j.pharmthera.2021.107926
Aleyah Goins 1 , Keisha Patel 1 , Sascha R A Alles 1
Affiliation  

The gabapentinoid drugs, gabapentin and pregabalin, are first-line treatments for neuropathic pain. The epidemics of chronic pain and opioid misuse have given rise to the widespread use of non-opioid drugs such as the gabapentinoids for treatment. Unfortunately, the widespread use of gabapentinoid drugs has resulted in reports of misuse and abuse. Here we summarize the clinical reports of gabapentinoid abuse in different patient populations to help inform clinical practice of chronic pain management.



中文翻译:

加巴喷丁类药物及其滥用潜力

加巴喷丁类药物加巴喷丁和普瑞巴林是治疗神经性疼痛的一线药物。慢性疼痛和阿片类药物滥用的流行已导致广泛使用非阿片类药物(如加巴喷丁类药物)进行治疗。不幸的是,加巴喷丁类药物的广泛使用导致了滥用和滥用的报告。在这里,我们总结了在不同患者群体中滥用加巴喷丁的临床报告,以帮助为慢性疼痛管理的临床实践提供信息。

更新日期:2021-06-24
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