To report a patient with impaired vision due to foveal involvement of toxoplasmic retinochoroiditis, who was successfully treated with intravitreal clindamycin and dexamethasone and oral therapy with azithromycin, trimethoprim-sulfamethoxazole, and prednisolone and led to successful visual and anatomic recovery. A 32-year-old man presented with three-day history of gradually decreasing visual acuity, redness, pain and photophobia of the right eye. Anterior chamber cellular reaction, vitritis and a white retinochoroiditis patch with adjacent retinal vasculitis in the fovea was suggestive of the toxoplasmic retinochoroiditis. He was treated with intravitreal clindamycin and dexamethasone injection followed by six-week regimen of azithromycin, trimethoprim-sulfamethoxazole, and prednisolone. In serial optical coherence tomography imaging, retinitis patch changed to cavitary foveal destruction. Fovea reorganized gradually, and visual acuity concurrently improved from counting finger 3 m to 20/25. In foveal toxoplasmic retinochoroiditis lesions, timely treatment is associated with retinal reorganization and visual improvement.

中文翻译：

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急性中心凹弓形体视网膜脉络膜炎治疗后的中心凹重组

报告一名因弓形虫性视网膜脉络膜炎受累而导致视力受损的患者，该患者成功接受玻璃体内注射克林霉素和地塞米松以及口服阿奇霉素、甲氧苄啶-磺胺甲恶唑和泼尼松龙治疗，视力和解剖结构恢复成功。一名 32 岁男性因右眼视力逐渐下降、发红、疼痛和畏光 3 天就诊。前房细胞反应、玻璃体炎和白色视网膜脉络膜炎斑块伴中央凹相邻视网膜血管炎提示弓形体视网膜脉络膜炎。他接受了玻璃体内注射克林霉素和地塞米松的治疗，随后接受了为期 6 周的阿奇霉素、甲氧苄啶-磺胺甲恶唑和泼尼松龙的治疗。在串行光学相干断层扫描成像中，视网膜炎贴片改为空洞性中央凹破坏。中央凹逐渐重组，视力同时从数指3m提高到20/25。在中心凹弓形体视网膜脉络膜炎病变中，及时治疗与视网膜重组和视力改善有关。