Background

The complete lockdown caused by the COVID-19 pandemic had imposed a new behavior and lifestyle especially in terms of diet, physical activity, and the management of patients with chronic diseases.

Aim

The present study aimed to analyze the impact of lockdown on the monitoring and care of type 2 diabetes mellitus (T2DM) patients in a Moroccan population from the Doukkala region.

Subjects and methods

We conducted a retrospective observational study including 121 T2DM patients recruited from the Diabetes Diagnosis and Treatment Center of El Jadida city. Demographic, anthropometric, and biochemical data of our T2DM patients were recorded before and after lockdown that lasted 82 days. All patients have signed an informed consent after being informed about the purely scientific aims of the study.

Results

Our sample involved 84 women and 37 men with an age average of 57.31 ± 0.91 years. The effects of lockdown were more marked in women than in men: women showed a significant tendency to gain weight (from 78.13 ± 1.36 kg to 81.80 ± 1.45 kg; p-value < 0.000), that impacted the body mass index (p-value < 0.000); they also showed significant increases in HbA1c values (p-value = 0.001), significant decrease in systolic blood pressure (p-value = 0.0302) and a surprising increase in high-density lipoprotein cholesterol (p-value = 0.0132). The prevalence of metabolic syndrome in the women sample increased from 46.4% to 54.8% after the lockdown. In men, the negative effect of lockdown was observed only in HbA1c that values increased significantly from 8.66 ± 0.21% to 9.51 ± 0.25% (p-value = 0.0127).

Conclusion

Our results reveal that lockdown had impacted negatively the health status of T2DM patients, especially women. We suggest an urgent development of programs aiming to improve the hygiene of life and to reduce the impact of future crises on patients suffering chronic diseases such as T2DM.

中文翻译：

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COVID-19 大流行：国家封锁对摩洛哥人群 2 型糖尿病患者健康状况的影响

背景

COVID-19 大流行造成的全面封锁带来了新的行为和生活方式，尤其是在饮食、体育活动和慢性病患者的管理方面。

目的

本研究旨在分析封锁对 Doukkala 地区摩洛哥人口中 2 型糖尿病 (T2DM) 患者的监测和护理的影响。

主题和方法

我们进行了一项回顾性观察研究，包括从 El Jadida 市糖尿病诊断和治疗中心招募的 121 名 T2DM 患者。我们的 T2DM 患者的人口统计学、人体测量学和生化数据是在持续 82 天的封锁前后记录的。所有患者在被告知研究的纯科学目的后都签署了知情同意书。

结果

我们的样本涉及 84 名女性和 37 名男性，平均年龄为 57.31 ± 0.91 岁。锁定对女性的影响比男性更显着：女性表现出显着的体重增加趋势（从 78.13 ± 1.36 公斤到 81.80 ± 1.45 公斤；p值 < 0.000），这会影响体重指数（p值< 0.000); 他们还显示 HbA1c 值显着增加（p值 = 0.001），收缩压显着降低（p值 = 0.0302）和高密度脂蛋白胆固醇惊人增加（p-值 = 0.0132）。封锁后，女性样本中代谢综合征的患病率从 46.4% 增加到 54.8%。在男性中，仅在 HbA1c 中观察到锁定的负面影响，其值从 8.66 ± 0.21% 显着增加到 9.51 ± 0.25%（p值 = 0.0127）。

结论

我们的结果表明，封锁对 T2DM 患者的健康状况产生了负面影响，尤其是女性。我们建议紧急制定旨在改善生活卫生并减少未来危机对患有 T2DM 等慢性病患者的影响的计划。