Abstract: As an emerging minimally invasive treatment method, percutaneous ablation is more and more widely used in the treatment of liver tumors. It has been recommended by guidelines for diagnosis and treatment of hepatocellular carcinoma (HCC) as a curative treatment alongside surgical resection and liver transplantation. In recent years, with the continuous advancement and innovation of percutaneous ablation technologies, their clinical efficacy and safety have been significantly improved, which has led to the expanded application of percutaneous ablation in the treatment of HCC—more and more patients who were previously considered unsuitable for ablation therapies are now being treated with percutaneous ablation. Obviously, percutaneous ablation can reduce the risk of treatment changes from curative strategies to palliative strategies. Based on clinical practice experience, this review enumerates the advantages and disadvantages of different ablative modalities and summarizes the existing combinations of ablation techniques, thus will help clinicians choose the most appropriate ablative modality for each patient and will provide scientific guidance for improving prognosis and making evidence-based treatment decisions. In addition, we point out the challenges and future prospects of the ablation therapies, thereby providing direction for future research.

Keywords: percutaneous ablation, hepatocellular carcinoma, assistive technology, image guidance

中文翻译：

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经皮消融治疗肝细胞癌面临的挑战：消融标准的扩展

摘要：经皮消融作为一种新兴的微创治疗方法，越来越广泛地应用于肝脏肿瘤的治疗。它已被肝细胞癌 (HCC) 的诊断和治疗指南推荐为与手术切除和肝移植一起的治愈性治疗方法。近年来，随着经皮消融技术的不断进步和创新，其临床疗效和安全性得到显着提高，导致经皮消融在HCC治疗中的应用不断扩大——越来越多的患者此前被认为不适合消融治疗现在正在接受经皮消融治疗。显然，经皮消融可以降低治疗策略从治愈性策略转变为姑息性策略的风险。本综述根据临床实践经验，列举了不同消融方式的优缺点，总结了现有的消融技术组合，以帮助临床医生为每一位患者选择最合适的消融方式，为改善预后和制定证据提供科学指导。 -基于治疗的决定。此外，我们指出了消融疗法的挑战和未来前景，从而为未来的研究提供了方向。从而帮助临床医生为每位患者选择最合适的消融方式，并为改善预后和做出循证治疗决策提供科学指导。此外，我们指出了消融疗法的挑战和未来前景，从而为未来的研究提供了方向。从而帮助临床医生为每位患者选择最合适的消融方式，并为改善预后和做出循证治疗决策提供科学指导。此外，我们指出了消融疗法的挑战和未来前景，从而为未来的研究提供了方向。

Keywords:经皮消融, 肝细胞癌, 辅助技术, 影像引导