• A facile ion-imprinting method (IIM) is used to synthesize the isolated Fe-N-C single-atomic site catalyst (IIM-Fe-SASC), which mimics the natural enzyme-like active site and shows excellent peroxidase-like activity.

• The ion-imprinting process can precisely control ion at the atomic level and form numerous well-defined single-atomic Fe-N-C sites.

• The IIM-Fe-SASC has been successfully used as the nanoprobe for in situ H₂O₂ detection generated from MDA-MB-231 cells.

中文翻译：

---

用于检测活细胞中过氧化氢的铁印迹单原子位点催化剂纳米探针

• 采用简便的离子印迹法 (IIM) 合成了分离的 Fe-NC 单原子位点催化剂 (IIM-Fe-SASC)，该催化剂模拟天然类酶活性位点，具有优异的类过氧化物酶活性。

• 离子印迹过程可以在原子水平上精确控制离子，形成许多定义明确的单原子 Fe-NC 位点。

• IIM-Fe-SASC 已成功用作纳米探针，用于原位检测 MDA-MB-231 细胞产生的H ₂ O _{2 。}