Our study aimed to examine the symptoms that might play a role in the co-occurrence of 9 DSM-5 symptom criteria of major depression among Brazil's adult population and healthcare professionals after three months of detecting the new coronavirus in Brazil. We estimated regularized Gaussian graphical models for both samples and compared the network structures. Depressed mood was the most central symptom in the general population network compared to the healthcare professional network. The findings revealed some individual symptoms showed a differential association between the general population and healthcare professionals. Those symptoms may be valuable targets for future research and treatment.

我们的研究旨在检查在巴西检测到新的冠状病毒三个月后，巴西成年人和医疗保健专业人员中重度抑郁症的 9 项 DSM-5 症状标准同时出现的症状。我们估计了两个样本的正则化高斯图模型并比较了网络结构。与医疗保健专业网络相比，抑郁情绪是普通人群网络中最核心的症状。研究结果显示，一些个体症状表明普通人群和医疗保健专业人员之间存在差异。这些症状可能是未来研究和治疗的有价值的目标。