This paper reports on the identification and full chemical characterization of the substance colloquially called “etonitazepyne” or “N-pyrrolidino etonitazene” (2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazole), a potent NPS opioid of the 5-nitrobenzimidazole class. Identification of etonitazepyne was performed, on a sample purchased during routine monitoring of the drug market, using GC-MS, HRAM LC-MS/MS, ¹H NMR, and FTIR. The chromatographic data, together with the FTIR data, indicated the presence of a highly pure compound and already indicated a benzimidazole structure. The specific benzimidazole regio-isomer was confirmed using ¹H NMR spectroscopy, resulting in the unambiguous identification of etonitazepyne.

中文翻译：

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在线销售的新型含吡咯烷基的 2-苄基苯并咪唑类阿片类药物“依托尼西平”的分析表征

本文报告了俗称“依托硝西平”或“ N-吡咯烷醇依托硝基”(2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl))的物质的鉴定和完整化学表征ethyl)-1 H -benzo[ d ]imidazole)，一种 5-硝基苯并咪唑类的强效 NPS 阿片类药物。使用 GC-MS、HRAM LC-MS/MS、¹ H NMR 和 FTIR 对药品市场常规监测期间购买的样品进行了依托硝西平的鉴定。色谱数据与 FTIR 数据一起表明存在高纯度化合物并已表明苯并咪唑结构。^使用1确认特定的苯并咪唑区域异构体H NMR光谱，导致明确鉴定依托硝西平。