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Near-infrared emission carbon dots for bio-imaging applications
New Carbon Materials ( IF 6.5 ) Pub Date : 2021-06-18 , DOI: 10.1016/s1872-5805(21)60041-0
Li-ping Li , Xiao-feng Ren , Pei-rong Bai , Yan Liu , Wei-yue Xu , Jun Xie , Rui-ping Zhang

It is very difficult to prepare red/near-infrared emission carbon dots (CDs) for bio-imaging applications which are needed because of their deep tissue penetration, minimal auto-fluorescence, and low emission light damage to bio-tissues. Near-infrared emitting CDs (NIR-CDs) were synthesized from sulfonated tetraphenylporphyrin using a solvothermal method. They have excitation-independent properties with a maximum emission at 692 nm. Studies showed that this unique near-infrared emission mainly originated from the aggregated molecular states of the CDs. The NIR-CDs showed good water solubility, exceptional biocompatibility, low toxicity, and superior cellular labelling ability. This work could significantly advance the structural design and preparation of NIR-CDs and corresponding bio-imaging applications.



中文翻译:

用于生物成像应用的近红外发射碳点

制备用于生物成像应用的红色/近红外发射碳点 (CD) 非常困难,因为它们具有深层组织穿透性、最小的自发荧光和对生物组织的低发射光损伤。使用溶剂热法从磺化四苯基卟啉合成近红外发射 CDs (NIR-CDs)。它们具有与激发无关的特性,最大发射波长为 692 nm。研究表明,这种独特的近红外发射主要源于 CD 的聚合分子状态。NIR-CDs 表现出良好的水溶性、卓越的生物相容性、低毒性和卓越的细胞标记能力。这项工作可以显着推进 NIR-CD 的结构设计和制备以及相应的生物成像应用。

更新日期:2021-06-19
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