Considering organic inhibitor plays a great role in preventing hydrate formation in oil and gas industry by shifting the hydrate phase equilibrium conditions, it is necessary to study the effects of organic inhibitors on the phase behavior of gas hydrates. In this study, a thermodynamic consistency-based model was developed to predict the phase equilibria of gas hydrates in methanol (MeOH), ethanol (EtOH), monoethylene glycol (MEG), diethylene glycol (DEG), triethylene glycol (TEG) and glycerol (GLY) solutions with concentrations of 5.44 wt%~ 65 wt%, respectively. The Chen-Guo model was applied to hydrate system. Compared with the original Hu-Lee-Sum correlation, a modified HLS type correlation that additionally considers the slight effect of temperature on calculating the activity of water was proposed. The prediction accuracy was characterized by the average absolute deviation in temperature (AADT). Results show that for CH₄ hydrate the Chen-Guo model coupled with HLS correlation performs as good as the original HLS correlation and PVTSim. The corresponding AADT for each organic inhibitor can be further decreased by at least 20.95% when using the Chen-Guo model coupled with the modified HLS type correlation. Besides, this modified model also shows a better performance in predicting the phase equilibria of C₂H₆ and CO₂ hydrates in the presence of these organic inhibitors than the Chen-Guo model coupled with HLS correlation do.

考虑到有机缓蚀剂通过改变水合物相平衡条件在油气工业中阻止水合物形成的重要作用，有必要研究有机缓蚀剂对天然气水合物相行为的影响。在这项研究中，开发了一种基于热力学一致性的模型来预测甲醇 (MeOH)、乙醇 (EtOH)、单乙二醇 (MEG)、二甘醇 (DEG)、三甘醇 (TEG) 和甘油中气体水合物的相平衡(GLY) 溶液，浓度分别为 5.44 wt%~65 wt%。Chen-Guo 模型应用于水合物系统。与原始的 Hu-Lee-Sum 相关性相比，提出了一种修正的 HLS 型相关性，它额外考虑了温度对计算水活度的轻微影响。预测精度的特点是温度的平均绝对偏差（AADT）。结果表明，对于 CH₄水合物 Chen-Guo 模型加上 HLS 相关的性能与原始 HLS 相关和 PVTSim 一样好。当使用 Chen-Guo 模型加上修正的 HLS 类型相关性时，每种有机抑制剂的相应 AADT 可以进一步降低至少 20.95%。此外，与具有HLS相关性的Chen-Guo模型相比，该改进模型在预测C ₂ H ₆和CO ₂水合物在这些有机抑制剂存在下的相平衡方面也表现出更好的性能。