Microplastics, as a new type of pollution, have attracted global attention and have become a research focus in recent years. Given the small size of microplastics, they can be ingested by many organisms. In addition, microplastics can enter the human body through the food chain. So, the potential dangers of microplastics can't be ignored. This study took Drosophila as a model organism to delve the physiological effects of polyethylene terephthalate microplastics (PET-MPs). Here, we reported that the higher concentration of PET-MPs was, the more obvious the effect became. The amount of oviposition decreased in female flies exposed, indicating that microplastics affected reproduction. PET-MPs caused the decrease of triglyceride and glucose content in male flies, as well as the decrease of starvation resistance, suggesting the effect of microplastics on energy metabolism. In addition, the 24-h spontaneous activity of flies exposed to PET-MPs increased significantly. The experimental results can help understand the potential impact of microplastics on physiology.

微塑料作为一种新型污染物质，引起了全球的关注，并成为近年来的研究热点。鉴于微塑料的体积很小，它们可以被许多生物摄入。此外，微塑料可以通过食物链进入人体。因此，微塑料的潜在危害不容忽视。本研究采用果蝇作为模型生物研究聚对苯二甲酸乙二醇酯微塑料 (PET-MPs) 的生理作用。在这里，我们报道了 PET-MPs 的浓度越高，效果越明显。暴露的雌性果蝇的产卵量减少，表明微塑料影响了繁殖。PET-MPs 导致雄性果蝇甘油三酯和葡萄糖含量降低，以及饥饿抵抗力降低，表明微塑料对能量代谢的影响。此外，暴露于 PET-MPs 的果蝇 24 小时自发活动显着增加。实验结果有助于了解微塑料对生理的潜在影响。