Cranial meningoencephalocele is a rare condition consisting of the herniation of meninges, CSF, and brain tissue through a cranial or skull base defect. Sphenoid sinus lateral recess meningoencephalocele is of particular interest due to the complex anatomy surrounding the bone defect and their demanding surgical management. In this technical note, we reported a step-by-step description of a rare case of sphenoid sinus lateral recess meningoencephalocele causing headache due to recurrent cerebrospinal fluid leak treated with a subtemporal craniotomy with extradural middle cranial fossa drilling and meningoencephalocele removal with multilayer reconstruction. The transcranial route is a safe and effective treatment for sphenoid sinus lateral recess meningoencephalocele repair. The subtemporal extradural approach allows for an optimal exposure of the relevant anatomy minimizing risks and improving the possibility to perform an effective multilayer skull base reconstruction.

颅脑膜脑膨出是一种罕见的疾病，包括脑膜、脑脊液和脑组织通过颅骨或颅底缺损突出。蝶窦侧隐窝脑膜脑膨出特别令人感兴趣，因为骨缺损周围的解剖结构复杂，手术治疗要求高。在本技术说明中，我们分步描述了罕见的蝶窦侧隐窝脑膜脑膨出病例，该病例因复发性脑脊液漏而引起头痛，采用颞下开颅硬膜外中颅窝钻孔和多层重建脑膜脑膨出切除术治疗。经颅入路是蝶窦侧隐窝脑膜脑膨出修复安全有效的治疗方法。