Sixteen-week-old female C57BL/6J mice were sacrificed aboard the International Space Station after 37 days of flight (RR-1 mission) and frozen carcasses returned to Earth. RNA was isolated from interscapular brown adipose tissue (BAT) and gonadal white adipose tissue (WAT). Spaceflight resulted in differential expression of genes in BAT consistent with increased non-shivering thermogenesis and differential expression of genes in WAT consistent with increased glucose uptake and metabolism, adipogenesis, and β-oxidation.

中文翻译：

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国际空间站上雌性 C57BL/6J 小鼠产热增加的证据

在飞行 37 天（RR-1 任务）后，16 周大的雌性 C57BL/6J 小鼠在国际空间站上被处死，冷冻尸体返回地球。从肩胛间棕色脂肪组织 (BAT) 和性腺白色脂肪组织 (WAT) 中分离出 RNA。航天飞行导致 BAT 中基因的差异表达与非颤抖产热增加一致，WAT 中基因的差异表达与葡萄糖摄取和代谢、脂肪生成和 β-氧化增加一致。