Assessing early erythrolysis and the relationship to perihematomal iron overload and white matter survival in human intracerebral hemorrhage,CNS Neuroscience & Therapeutics

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Assessing early erythrolysis and the relationship to perihematomal iron overload and white matter survival in human intracerebral hemorrhage
CNS Neuroscience & Therapeutics ( IF 4.8 ) Pub Date : 2021-06-17 , DOI: 10.1111/cns.13693
Nemanja Novakovic ₁ , Zachary M Wilseck ₂ , Thomas L Chenevert ₂ , Guohua Xi ₁ , Richard F Keep ₁ , Aditya S Pandey _{1,

2} , Neeraj Chaudhary _{1,

2,

3}

Affiliation

Iron released from lysed red blood cells within the hematoma plays a role in intracerebral hemorrhage (ICH)-related neurotoxicity. This study utilizes magnetic resonance imaging (MRI) to examine the time course, extent of erythrolysis, and its correlation with perihematomal iron accumulation and white matter loss.

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