Effective anticancer adoptive cellular therapy (ACT) requires sufficient infiltration of injected cytotoxic lymphocytes, but pathophysiology frustrates this. Regulator of G protein signaling 1 limits T cell trafficking to breast tumors and may be targeted to improve ACT.

中文翻译：

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“注意差距”：RGS1 阻碍抗肿瘤淋巴细胞


有效的抗癌过继细胞疗法（ACT）需要注射的细胞毒性淋巴细胞的充分浸润，但病理生理学阻碍了这一点。 G 蛋白信号传导调节剂 1 限制 T 细胞向乳腺肿瘤的运输，并可能有针对性地改善 ACT。