Although non-suicidal self-injury (NSSI) is an issue of major concern to colleges worldwide, we lack detailed information about the epidemiology of NSSI among college students. The objectives of this study were to present the first cross-national data on the prevalence of NSSI and NSSI disorder among first-year college students and its association with mental disorders.

Data come from a survey of the entering class in 24 colleges across nine countries participating in the World Mental Health International College Student (WMH-ICS) initiative assessed in web-based self-report surveys (20 842 first-year students). Using retrospective age-of-onset reports, we investigated time-ordered associations between NSSI and Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-IV) mood (major depressive and bipolar disorder), anxiety (generalized anxiety and panic disorder), and substance use disorders (alcohol and drug use disorder).

NSSI lifetime and 12-month prevalence were 17.7% and 8.4%. A positive screen of 12-month DSM-5 NSSI disorder was 2.3%. Of those with lifetime NSSI, 59.6% met the criteria for at least one mental disorder. Temporally primary lifetime mental disorders predicted subsequent onset of NSSI [median odds ratio (OR) 2.4], but these primary lifetime disorders did not consistently predict 12-month NSSI among respondents with lifetime NSSI. Conversely, even after controlling for pre-existing mental disorders, NSSI consistently predicted later onset of mental disorders (median OR 1.8) as well as 12-month persistence of mental disorders among students with a generalized anxiety disorder (OR 1.6) and bipolar disorder (OR 4.6).

NSSI is common among first-year college students and is a behavioral marker of various common mental disorders.

尽管非自杀性自伤（NSSI）是全世界大学关注的一个问题，但我们缺乏有关大学生中 NSSI 流行病学的详细信息。本研究的目的是提供关于一年级大学生中 NSSI 和 NSSI 障碍的患病率及其与精神障碍的关系的第一份跨国数据。

数据来自对参与世界心理健康国际大学生 (WMH-ICS) 倡议的 9 个国家 24 所大学的新生进行的一项调查，该调查通过基于网络的自我报告调查进行评估（20 842 名一年级学生）。使用回顾性发病年龄报告，我们研究了 NSSI 与《精神疾病诊断和统计手册》第五版 (DSM-IV) 情绪（重度抑郁和双相情感障碍）、焦虑（广泛性焦虑和惊恐障碍）之间的时间顺序关联和物质使用障碍（酒精和药物使用障碍）。

NSSI 终生患病率和 12 个月患病率分别为 17.7% 和 8.4%。12 个月 DSM-5 NSSI 障碍筛查阳性率为 2.3%。在终生患有 NSSI 的人中，59.6% 符合至少一种精神障碍的标准。暂时性原发性终生精神障碍可预测随后发生 NSSI [中位比值比 (OR) 2.4]，但这些原发性终生精神障碍并不能一致地预测终生 NSSI 受访者中的 12 个月 NSSI。相反，即使在控制了先前存在的精神障碍之后，NSSI 一致预测了患有广泛性焦虑症 (OR 1.6) 和双向情感障碍的学生精神障碍的较晚发作（中位 OR 1.8）以及精神障碍 12 个月的持续时间（OR 1.6）。或 4.6）。

NSSI 在一年级大学生中很常见，是各种常见精神障碍的行为标志。