To describe the audio-vestibular disorders related to the newly SARS-CoV-2 infection, including the possible ototoxicity side-effects related to the use of drugs included in the SARS-CoV-2 treatment protocols. A systematic review was performed according to the PRISMA protocol. The Medline and Embase databases were searched from March 1, 2020 to April 9, 2021. Initially the search yielded 400 manuscripts, which were reduced to 15, upon the application of inclusion criteria. Sensorineural hearing loss (SNHL) is the most frequent audio-vestibular symptom described, occurring alone or in association with tinnitus and vertigo. The etiopathogenesis of the inner ear disorders related to COVID-19 infection is still poorly understood. The number of reports of COVID-19 infections associated to audio-vestibular disorders is increasing; even if the quality of the studies available is often insufficient, audio-vestibular disorders should be considered as possible manifestations to be included among the symptoms of this infection.

描述与新的 SARS-CoV-2 感染相关的音频前庭疾病，包括与使用 SARS-CoV-2 治疗方案中包含的药物相关的可能的耳毒性副作用。根据 PRISMA 协议进行系统评价。 Medline 和 Embase 数据库的检索时间为 2020 年 3 月 1 日至 2021 年 4 月 9 日。最初检索出 400 篇稿件，在应用纳入标准后减少到 15 篇。感音神经性听力损失（SNHL）是最常见的听觉前庭症状，单独发生或与耳鸣和眩晕相关。与 COVID-19 感染相关的内耳疾病的发病机制仍知之甚少。与听觉前庭疾病相关的 COVID-19 感染的报告数量正在增加；即使现有研究的质量往往不足，也应将听觉前庭障碍视为可能的表现，纳入这种感染的症状中。