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Blood gas bilirubin measurements in neonates must be adjusted for HbF to avoid misleading results
Fetal & Neonatal ( IF 3.9 ) Pub Date : 2021-06-18 , DOI: 10.1136/archdischild-2021-322071
Niranjan Thomas 1 , Alan McNeil 2 , Clare Louise Collins 3
Affiliation  

Hyperbilirubinaemia is common in the first week of life with 60%–80% of babies developing jaundice.1 Though usually uncomplicated, untreated hyperbilirubinaemia, can lead to irreversible neurological injury.2 Prevention of bilirubin-induced neurological dysfunction (BIND) includes universal risk factor and clinical assessment with additional transcutaneous bilirubinometer or Total serum bilirubin (TSB) assessment.1 Point of care testing (POCT) has the advantage of rapid bedside results, improving outcomes. Bilirubin measurement is available as a POCT via blood gas analysers in most neonatal intensive care units (NICU). Studies have shown good accuracy and precision of blood gas bilirubin compared with standard serum bilirubin assessment.3 4 A blood gas machine (Radiometer ABL 800 flex) was installed by the company in a new level 3 NICU in Australia and calibrated by the …

中文翻译:

必须针对 HbF 调整新生儿的血气胆红素测量值以避免误导性结果

高胆红素血症在出生后的第一周很常见,有 60%–80% 的婴儿出现黄疸。 1 虽然高胆红素血症通常不复杂,未经治疗,但可导致不可逆的神经损伤。 2 预防胆红素诱导的神经功能障碍 (BIND) 包括普遍的危险因素和额外的经皮胆红素计或总血清胆红素 (TSB) 评估的临床评估。1 护理点检测 (POCT) 具有快速床旁结果的优势,可改善结果。在大多数新生儿重症监护病房 (NICU) 中,胆红素测量可通过血气分析仪作为 POCT 进行。研究表明,与标准血清胆红素评估相比,血气胆红素的准确度和精密度更高。
更新日期:2021-06-18
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