Objective:

Examine associations between oral psychostimulant pharmacotherapy adherence, work productivity, and related indirect costs among US adults with ADHD.

Methods:

Medication adherence (Medication Adherence Reasons Scale [MAR-Scale]), work productivity and activity impairment (Work Productivity and Activity Impairment–General Health questionnaire), and ADHD symptom level (Adult ADHD Self-Report Scale version 1.1 Symptom Checklist) were assessed in this noninterventional online survey of adults who self-reported having an ADHD diagnosis and were currently receiving oral psychostimulant treatment for ≥3 months.

Results:

Of 602 respondents, 395 had low/medium adherence (LMA: MAR-Scale total score ≥1) and 207 had high adherence (HA: MAR-Scale total score 0). After adjusting for covariates, the LMA group had significantly greater levels of absenteeism, absenteeism-related indirect costs, and total indirect costs (all p < .01) than the HA group.

Conclusion:

In adults with ADHD using oral psychostimulants, lower medication adherence was associated with greater absenteeism and indirect costs.

中文翻译：

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成人多动症患者口服兴奋剂药物依从性与工作效率的关系

客观的：

检查美国 ADHD 成人的口服精神兴奋剂药物治疗依从性、工作效率和相关间接成本之间的关联。

方法：

药物依从性（药物依从性原因量表 [MAR-Scale]）、工作效率和活动障碍（工作效率和活动障碍-一般健康问卷）和 ADHD 症状水平（成人 ADHD 自我报告量表版本 1.1 症状检查表）在这项针对自我报告患有 ADHD 诊断并且目前正在接受口服精神兴奋剂治疗≥3 个月的成年人进行的非干预性在线调查。

结果：

在 602 名受访者中，395 人依从性低/中等（LMA：MAR-Scale 总分≥1），207 人依从性高（HA：MAR-Scale 总分 0）。调整协变量后，LMA 组的缺勤率、缺勤相关间接成本和总间接成本（均p  < .01）显着高于 HA 组。

结论：

在使用口服精神兴奋剂的 ADHD 成人中，较低的药物依从性与较高的缺勤率和间接成本相关。