当前位置: X-MOL 学术J. Leukoc. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
What a difference ADA2 makes: Insights into the pathophysiology of ADA2 deficiency from single-cell RNA sequencing of monocytes
Journal of Leukocyte Biology ( IF 5.5 ) Pub Date : 2021-06-16 , DOI: 10.1002/jlb.5ce0421-186r
Lisa Ehlers 1 , Isabelle Meyts 2
Affiliation  

Discussion on the increase in nonclassical monocytes in patients with DADA2 as shown by scRNA seq; these pro inflammatory cells also show increased TNFR2, type I, and type II IFN pathway gene expression.
image


中文翻译:

ADA2 有何不同:从单核细胞的单细胞 RNA 测序洞察 ADA2 缺乏症的病理生理学

scRNA seq显示DADA2患者非经典单核细胞增多的讨论;这些促炎细胞还显示出 TNFR2、I 型和 II 型 IFN 通路基因表达增加。
图片
更新日期:2021-06-16
down
wechat
bug