当前位置: X-MOL 学术Respir. Physiol. Neurobiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The impact of nasal adhesions on airflow and mucosal cooling – A computational fluid dynamics analysis
Respiratory Physiology & Neurobiology ( IF 2.3 ) Pub Date : 2021-06-17 , DOI: 10.1016/j.resp.2021.103719
Praween Senanayake 1 , Hana Salati 2 , Eugene Wong 2 , Kimberley Bradshaw 1 , Yidan Shang 2 , Narinder Singh 3 , Kiao Inthavong 2
Affiliation  

Nasal adhesions are a known postoperative complication following surgical procedures for nasal airway obstruction (NAO); and are a common cause of surgical failure, with patients often reporting significant NAO, despite relatively minor adhesion size. Division of such nasal adhesions often provides much greater relief than anticipated, based on the minimal reduction in cross-sectional area associated with the adhesion. The available literature regarding nasal adhesions provides little evidence examining their quantitative and qualitative effects on nasal airflow using objective measures. This study examined the impact of nasal adhesions at various anatomical sites on nasal airflow and mucosal cooling using computational fluid dynamics (CFD). A high-resolution CT scan of the paranasal sinuses of a 25-year-old, healthy female patient was segmented to create a three-dimensional nasal airway model. Virtual nasal adhesions of 2.5 mm diameter were added to various locations within the nasal cavity, representing common sites seen following NAO surgery. A series of models with single adhesions were created. CFD analysis was performed on each model and compared with a baseline no-adhesion model, comparing airflow and heat and mass transfer. The nasal adhesions resulted in no significant change in bulk airflow patterns through the nasal cavity. However, significant changes were observed in local airflow and mucosal cooling around and immediately downstream to the nasal adhesions. These were most evident with anterior nasal adhesions at the internal valve and anterior inferior turbinate. Postoperative nasal adhesions create local airflow disruption, resulting in reduced local mucosal cooling on critical surfaces, explaining the exaggerated perception of nasal obstruction. In particular, anteriorly located adhesions created greater disruption to local airflow and mucosal cooling, explaining their associated greater subjective sensation of obstruction.



中文翻译:

鼻粘连对气流和黏膜冷却的影响——计算流体动力学分析

鼻粘连是鼻气道阻塞 (NAO) 外科手术后已知的术后并发症;并且是手术失败的常见原因,尽管粘连面积相对较小,但患者经常报告明显的 NAO。基于与粘连相关的横截面积的最小减少,这种鼻粘连的分割通常提供比预期更大的缓解。现有的关于鼻粘连的文献几乎没有提供证据来检查它们使用客观测量对鼻气流的定量和定性影响。本研究使用计算流体动力学 (CFD) 检查了不同解剖部位的鼻腔粘连对鼻气流和粘膜冷却的影响。对一名 25 岁的鼻窦进行高分辨率 CT 扫描,对健康女性患者进行分割,创建三维鼻气道模型。将直径为 2.5 毫米的虚拟鼻粘连添加到鼻腔内的不同位置,代表 NAO 手术后常见的部位。创建了一系列具有单一粘连的模型。对每个模型进行 CFD 分析,并与基线无粘附模型进行比较,比较气流和传热传质。鼻粘连导致通过鼻腔的大量气流模式没有显着变化。然而,在鼻粘连周围和紧邻下游的局部气流和粘膜冷却中观察到显着变化。这些在内瓣和前下鼻甲处的前鼻粘连最为明显。术后鼻粘连造成局部气流中断,导致关键表面的局部粘膜冷却减少,解释了对鼻塞的夸大感知。特别是,位于前方的粘连对局部气流和粘膜冷却造成更大的破坏,这解释了它们相关的更大的阻塞主观感觉。

更新日期:2021-06-29
down
wechat
bug