The aim of this work is to summarize and evaluate the current status of knowledge on flattening filter free (FFF) beams and their applications in stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). A PubMed search was undertaken in order to identify relevant publications using FFF and stereotactic radiotherapy as keywords. On a clinical aspect, lung tumors treated with FFF SBRT show promising results in terms of local control and overall survival with acute toxicities consistent with those that occur with standard radiotherapy. Beside lung, SBRT is suitable for different anatomical sites such as liver, prostate, cervix, etc. offering similar results: reduced treatment time, good tumor control and mild acute toxicities. Regarding brain tumors, the employment of SRS with FFF beams significantly reduces treatment time and provides notable normal tissue sparing due to the sharp dose fall-off outside the tumor.

这项工作的目的是总结和评估关于展平无滤波器 (FFF) 光束的知识现状及其在立体定向放射外科 (SRS) 和立体定向放射治疗 (SBRT) 中的应用。进行了 PubMed 搜索，以确定使用 FFF 和立体定向放射治疗作为关键字的相关出版物。在临床方面，用 FFF SBRT 治疗的肺肿瘤在局部控制和总生存率方面显示出有希望的结果，急性毒性与标准放疗发生的毒性一致。除了肺，SBRT 适用于不同的解剖部位，如肝脏、前列腺、子宫颈等，提供相似的结果：缩短治疗时间、良好的肿瘤控制和轻微的急性毒性。关于脑肿瘤，