Childhood is a period where most vaccines are administered in order to build-up immunological memory, and immunization against vaccine-preventable diseases is an essential part of child care and health. The administration of vaccines to children with inflammatory diseases is a frequent point of concern for parents and physicians. Published information on the relation between vaccines and autoinflammatory diseases of the central nervous system (CNS) consists of case and cohort studies and reviews, in great majority on adult patients. Vaccines do not have any established causative or triggering effects on these diseases. Another issue is the immunization schedule of patients with autoinflammatory CNS diseases, specifically the interactions between the disorder, the clinical status, the treatment and the vaccine. In this review, we summarize the existing information between autoinflammatory disorders of the CNS and vaccines in childhood and underline the points to be considered under various treatment regimens.

儿童时期是接种大多数疫苗以建立免疫记忆的时期，针对疫苗可预防疾病的免疫接种是儿童保育和健康的重要组成部分。为患有炎症性疾病的儿童接种疫苗是父母和医生经常关注的问题。已发表的关于疫苗与中枢神经系统 (CNS) 自身炎症性疾病之间关系的信息包括病例和队列研究以及评论，其中绝大多数针对成人患者。疫苗对这些疾病没有任何既定的致病或触发作用。另一个问题是自身炎症性 CNS 疾病患者的免疫计划，特别是疾病、临床状态、治疗和疫苗之间的相互作用。在这次审查中，