Novel composites based on natural zeolite—clinoptilolite and monoterpene phenols—thymol and carvacrol were prepared by supercritical solvent impregnation (SSI) in supercritical carbon dioxide (scCO₂) at 30 MPa and 35 °C during 18 h. The content of phenols in composites (thymol—23.0 and carvacrol—19.1 wt%) was determined using both C,H,N and thermal analysis (TGA); interactions of the phenols with the zeolite lattice studied by Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (PXRD) showed that the zeolite lattice was preserved in the composites. The composites exhibited antibacterial activity toward Gram-negative bacteria Escherichia coli DSM 498 and Gram-positive bacteria Staphylococcus aureus ATCC 25923 in different water media (phosphate buffer solution, spring water and lake water). After 1 h carvacrol-containing clinoptilolite showed better antibacterial activity than composite with thymol. Both composites expressed bactericidal effect after 24 h of contact. Leaching of the phenols from composite in water was more pronounced from thymol (22.7–32.1%) than for carvacrol (6.2–8.9%) suggesting influence of steric effect on the desorption process.

基于天然沸石——斜发沸石和单萜酚——百里酚和香芹酚的新型复合材料通过超临界溶剂浸渍 (SSI) 在30 MPa 和 35 °C 的超临界二氧化碳 (scCO ₂ )中制备18 小时。复合材料中苯酚的含量（百里酚 - 23.0 和香芹酚 - 19.1 wt%）使用 C、H、N 和热分析 (TGA) 测定；通过傅里叶变换红外光谱 (FTIR) 和粉末 X 射线衍射 (PXRD) 研究苯酚与沸石晶格的相互作用表明，复合材料中保留了沸石晶格。复合材料对革兰氏阴性菌大肠杆菌DSM 498 和革兰氏阳性菌金黄色葡萄球菌具有抗菌活性ATCC 25923 在不同的水介质（磷酸盐缓冲溶液、泉水和湖水）中。1 小时后，含有香芹酚的斜发沸石显示出比与百里酚复合物更好的抗菌活性。两种复合材料在接触 24 小时后都表现出杀菌作用。百里香酚 (22.7–32.1%) 比香芹酚 (6.2–8.9%) 更明显地从复合材料中浸出酚类，这表明空间效应对解吸过程的影响。