Background:

The association between a lifetime history of sexual victimization and the well-being of women during the perinatal period has received increasing attention. However, research investigating this relationship has yet to be systematically reviewed or quantitatively synthesized.

Aim:

This systematic review and meta-analysis aims to calculate the pooled effect size estimate of the statistical association between a lifetime history of sexual victimization and perinatal depression (PND).

Method:

Four bibliographic databases were systematically searched, and reference harvesting was conducted to identify peer-reviewed articles that empirically examined associations between a lifetime history of sexual victimization and PND. A random effects model was used to ascertain an overall pooled effect size estimate in the form of an odds ratio and corresponding 95% confidence intervals (CIs). Subgroup analyses were also conducted to assess whether particular study features and sample characteristic (e.g., race and ethnicity) influenced the magnitude of effect size estimates.

Results:

This review included 36 studies, with 45 effect size estimates available for meta-analysis. Women with a lifetime history of sexual victimization had 51% greater odds of experiencing PND relative to women with no history of sexual victimization (OR = 1.51, 95% CI [1.35, 1.67]). Effect size estimates varied considerably according to the PND instrument used in each study and the racial/ethnic composition of each sample.

Conclusion:

Findings provide compelling evidence for an association between a lifetime history of sexual victimization and PND. Future research should focus on screening practices and interventions that identify and support survivors of sexual victimization perinatally.

中文翻译：

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终生性受害史与围产期抑郁症的关系：系统回顾和荟萃分析

背景：

一生的性受害史与围产期妇女的福祉之间的关联越来越受到关注。然而，调查这种关系的研究尚未得到系统审查或定量综合。

目的：

本系统评价和荟萃分析旨在计算终生性受害史与围产期抑郁症 (PND) 之间统计关联的合并效应量估计值。

方法：

系统地搜索了四个书目数据库，并进行了参考收集，以确定同行评审的文章，这些文章凭经验检查了一生的性受害史与 PND 之间的关联。使用随机效应模型以比值比和相应的 95% 置信区间 (CI) 的形式确定总体合并效应量估计值。还进行了亚组分析以评估特定研究特征和样本特征（例如，种族和民族）是否影响效应量估计的大小。

结果：

该综述包括 36 项研究，其中 45 项效应量估计值可用于荟萃分析。与没有性受害史的女性相比，有终生性受害史的女性患 PND 的几率高 51%（OR = 1.51, 95% CI [1.35, 1.67]）。根据每项研究中使用的 PND 工具和每个样本的种族/民族构成，影响大小估计有很大差异。

结论：

调查结果为终生性受害史与 PND 之间的关联提供了令人信服的证据。未来的研究应侧重于识别和支持围产期性受害幸存者的筛查实践和干预措施。