Abstract

Background: In the context of obesity, little is known about the prevalence of food addiction nor about the phenotype of obese patients with food addiction. Objectives: To assess: (i) the prevalence of food addiction among obese patients eligible for obesity surgery; (ii) the relationship between clinical features and the complications of obesity. Methods: Consecutive patients consulting for the first time were included. The Yale Food Addiction Scale (YFAS) 2.0 questionnaire was used to diagnose food addiction and its severity. Demographics, clinical features, and obesity complications were systematically collected. Statistics: Student's test was used for numerical variables and Chi-square test or Fisher’s exact test for categorical variables. Results: A total of 292 patients were included: 79% female, age (mean ± SD) 42.6 ± 13.0 yrs., body mass index (BMI) 43.2 ± 6.8 kg/m². One hundred and eight patients (37%) had food addiction: 58% severe, 33% moderate, 9% mild. Food addiction prevalence was 39% (n = 61/156) among patients eligible for obesity surgery. Food addiction was more frequent among the unemployed, compared to professionally active patients (41.0% vs. 33.5%, p = 0.046). Clinical and metabolic phenotypes and obesity complications were similar between patients with and without food addiction. Conclusion: Food addiction was present in 37% of obese patients, but was not associated with clinical features or obesity complications. Therefore, it should be systemically assessed for appropriate management.

摘要

背景：在肥胖的背景下，人们对食物成瘾的患病率和食物成瘾肥胖患者的表型知之甚少。目的：评估： (i) 符合肥胖手术条件的肥胖患者的食物成瘾流行率；(ii) 临床特征与肥胖并发症的关系。方法：纳入首次就诊的连续患者。耶鲁食物成瘾量表（YFAS）2.0问卷用于诊断食物成瘾及其严重程度。系统地收集了人口统计学、临床特征和肥胖并发症。统计数据：学生检验用于数值变量，卡方检验或 Fisher 精确检验用于分类变量。结果：共纳入 292 名患者：79% 为女性，年龄（平均值 ± SD）42.6 ± 13.0 岁，体重指数（BMI） 43.2 ± 6.8 kg/m ²。108 名患者 (37%) 有食物成瘾：58% 重度，33% 中度，9% 轻度。在符合肥胖手术条件的患者中，食物成瘾患病率为 39%（n = 61/156）。与从事职业活动的患者相比，失业者的食物成瘾更为常见（41.0%对33.5%，p = 0.046）。有和没有食物成瘾的患者之间的临床和代谢表型以及肥胖并发症相似。结论： 37% 的肥胖患者存在食物成瘾，但与临床特征或肥胖并发症无关。因此，应对其进行系统评估以进行适当的管理。