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EXTENDED ABSORPTION OF LIOTHYRONINE FROM POLY-ZINC-LIOTHYRONINE (PZL) IN HUMANS
medRxiv - Endocrinology Pub Date : 2021-06-15 , DOI: 10.1101/2021.06.14.21258437
Alexandra M. Dumitrescu , Erin C. Hanlon , Marilyn Arosemena , Olga Duchon , Matthew Ettleson , Mihai Giurcanu , Antonio C. Bianco

Background Liothyronine (LT3) has been increasingly used in combination with levothyroxine (LT4) in the treatment of hypothyroidism. A metal coordinated form of LT3, known as poly-zinc-liothyronine (PZL), avoided in rats the typical T3 peak seen after oral administration of LT3.

中文翻译:

人体内从聚锌碘酒 (PZL) 中延长碘酒的吸收

背景碘甲状腺氨酸 (LT3) 越来越多地与左甲状腺素 (LT4) 联合用于治疗甲状腺功能减退症。LT3 的金属配位形式,称为聚锌碘塞罗宁 (PZL),避免了大鼠口服 LT3 后出现的典型 T3 峰。
更新日期:2021-06-25
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