The context and purpose of the study are as follows: Drug-borne infections may arise from non-adherence to strict microbiological quality of pharmaceuticals products. Moreover, presence of exceeding levels of microorganisms in non-sterile pharmaceuticals may lead to change of their organoleptic characteristics and loss of effectiveness. The aim of the study is to evaluate the microbiological quality of commonly used non-sterile pharmaceuticals in Alexandria, Egypt. Average microbiological quality of the studied products, where 17.03% and 19.23 % of samples had exceeded the maximum acceptable limit of TAMC and TYMC, respectively. No E. coli was isolated from oral products. None of S. aureus nor P. aeruginosa were isolated from topical products. Bacterial growth was recovered from 19 (10.44%) of the studied 182 samples, four Bacillus spp. had been recovered from topical products, two P. aeruginosa isolates were recovered from tablets and other two were isolated from syrups dosage forms. Other isolates were Pseudomonas stutzeri, Stenotrophomonas maltophilia, Acinetobacter Achromobacter denitrificans, Ochrobactrum anthropic and Aeromonas salmonicida. Average microbiological quality of the tested pharmaceuticals used in Alexandria.

中文翻译：

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埃及非无菌药品的微生物质量

该研究的背景和目的如下： 药物传播感染可能源于不遵守严格的药品微生物质量。此外，在非无菌药物中存在超过水平的微生物可能会导致其感官特性的改变和有效性的丧失。该研究的目的是评估埃及亚历山大市常用非无菌药物的微生物质量。研究产品的平均微生物质量，其中 17.03% 和 19.23% 的样品分别超过了 TAMC 和 TYMC 的最大可接受限度。没有从口服产品中分离出大肠杆菌。金黄色葡萄球菌和铜绿假单胞菌均未从外用产品中分离出来。从所研究的 182 个样品中的 19 个 (10.44%) 中恢复了细菌生长，其中四种芽孢杆菌属。从外用产品中回收到两种铜绿假单胞菌分离株，从片剂中分离出两种铜绿假单胞菌，另外两种从糖浆剂型中分离出来。其他分离株是施氏假单胞菌、嗜麦芽窄食单胞菌、无色不动杆菌反硝化菌、人嗜铬杆菌和杀鲑气单胞菌。亚历山大使用的测试药物的平均微生物质量。