Background: Little is known about how knowledge brokers (KBs) operate in low- and middle-income countries (LMICs) to translate evidence for health policy and practice. These intermediaries facilitate relationships between evidence producers and users to address public health issues. Aims and objectives: To increase understanding, a mixed-methods study collected data from KBs who had acted on evidence from the 2015 Global Maternal Newborn Health Conference in Mexico. Methods: Of the 1000 in-person participants, 252 plus 72 online participants (n=324) from 56 countries completed an online survey, and 20 participants from 15 countries were interviewed. Thematic analysis and application of knowledge translation (KT) theory explored factors influencing KB actions leading to evidence uptake. Descriptive statistics of respondent characteristics were used for cross-case comparison. Findings: Results suggest factors supporting the KB role in evidence uptake, which include active relationships with evidence users through embedded KB roles, targeted and tailored evidence communication to fit the context, user receptiveness to evidence from a similar country setting, adaptability in the KB role, and action orientation of KBs. Discussion and conclusions: Initiatives to increase evidence uptake in LMICs should work to establish supportive structures for embedded KT, identify processes for ongoing cross-country learning, and strengthen KBs already showing effectiveness in their roles.

中文翻译：

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“也许我们可以扭转局面”：一项解释性混合方法研究，以了解知识经纪人如何在低收入和中等收入国家动员健康证据

背景：知识经纪人 (KB) 如何在低收入和中等收入国家 (LMIC) 中运作以将证据转化为卫生政策和实践知之甚少。这些中介机构促进了证据制作者和使用者之间的关系，以解决公共卫生问题。目的和目标：为了增进了解，一项混合方法研究从 2015 年在墨西哥举行的全球孕产妇新生儿健康会议上根据证据采取行动的知识分子收集了数据。方法：在 1000 名面对面参与者中，来自 56 个国家的 252 名和 72 名在线参与者（n=324）完成了在线调查，并对来自 15 个国家的 20 名参与者进行了采访。知识翻译 (KT) 理论的主题分析和应用探索了影响知识转化行动导致证据吸收的因素。受访者特征的描述性统计用于跨案例比较。结果：结果表明支持知识库在证据吸收中的作用的因素，包括通过嵌入式知识库角色与证据用户建立积极的关系、有针对性和量身定制的证据交流以适应上下文、用户对来自类似国家环境的证据的接受度、知识库角色的适应性，以及知识库的行动导向。讨论和结论：旨在增加 LMICs 证据吸收的举措应该致力于为嵌入式 KT 建立支持结构，确定正在进行的跨国学习的过程，并加强已经在其作用中显示出有效性的知识库。其中包括通过嵌入式知识库角色与证据用户建立积极关系、有针对性和量身定制的证据交流以适应上下文、用户对来自类似国家环境的证据的接受度、知识库角色的适应性以及知识库的行动导向。讨论和结论：旨在增加 LMICs 证据吸收的举措应该致力于为嵌入式 KT 建立支持结构，确定正在进行的跨国学习的过程，并加强已经在其作用中显示出有效性的知识库。其中包括通过嵌入式知识库角色与证据用户建立积极关系、有针对性和量身定制的证据交流以适应上下文、用户对来自类似国家环境的证据的接受度、知识库角色的适应性以及知识库的行动导向。讨论和结论：旨在增加 LMICs 证据吸收的举措应该致力于为嵌入式 KT 建立支持结构，确定正在进行的跨国学习的过程，并加强已经在其作用中显示出有效性的知识库。