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Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes
IEEE Open Journal of Engineering in Medicine and Biology ( IF 2.7 ) Pub Date : 2021-05-11 , DOI: 10.1109/ojemb.2021.3078843
Krishna K Ramajayam 1 , A Marissa Wolfe 2 , Anjan Motamarry 1 , Georges J Nahhas 3, 4 , John Yost 5 , Michael J Yost 5 , Dieter Haemmerich 1
Affiliation  

Untargeted large volume hyperthermia (HT) rapidly depletes systemically available thermosensitive liposome-encapsulated drug, resulting in low tumor drug uptake. Computer models established the cause for the observed differences in tumor drug uptake for varying HT methods.

中文翻译:


无针对性的大容量热疗减少了热敏脂质体中肿瘤药物的摄取



无针对性的大容量热疗 (HT) 会迅速耗尽全身可用的热敏脂质体封装药物,导致肿瘤药物摄取低。计算机模型确定了不同 HT 方法观察到的肿瘤药物摄取差异的原因。
更新日期:2021-05-11
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