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Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes
IEEE Open Journal of Engineering in Medicine and Biology ( IF 2.7 ) Pub Date : 2021-05-11 , DOI: 10.1109/ojemb.2021.3078843 Krishna K Ramajayam 1 , A Marissa Wolfe 2 , Anjan Motamarry 1 , Georges J Nahhas 3, 4 , John Yost 5 , Michael J Yost 5 , Dieter Haemmerich 1
IEEE Open Journal of Engineering in Medicine and Biology ( IF 2.7 ) Pub Date : 2021-05-11 , DOI: 10.1109/ojemb.2021.3078843 Krishna K Ramajayam 1 , A Marissa Wolfe 2 , Anjan Motamarry 1 , Georges J Nahhas 3, 4 , John Yost 5 , Michael J Yost 5 , Dieter Haemmerich 1
Affiliation
Untargeted large volume hyperthermia (HT) rapidly depletes systemically available thermosensitive liposome-encapsulated drug, resulting in low tumor drug uptake. Computer models established the cause for the observed differences in tumor drug uptake for varying HT methods.
中文翻译：
无针对性的大容量热疗减少了热敏脂质体中肿瘤药物的摄取
无针对性的大容量热疗 (HT) 会迅速耗尽全身可用的热敏脂质体封装药物，导致肿瘤药物摄取低。计算机模型确定了不同 HT 方法观察到的肿瘤药物摄取差异的原因。
更新日期：2021-05-11
中文翻译：
无针对性的大容量热疗减少了热敏脂质体中肿瘤药物的摄取
无针对性的大容量热疗 (HT) 会迅速耗尽全身可用的热敏脂质体封装药物，导致肿瘤药物摄取低。计算机模型确定了不同 HT 方法观察到的肿瘤药物摄取差异的原因。
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