Abstract

Introduction

Pertussis is a highly contagious respiratory disease that results in disproportionate morbidity and mortality in infants who have yet to receive the primary diphtheria-tetanus-pertussis vaccine series. In the preceding decades numerous countries began to pursue either prenatal vaccination of pregnant women or postpartum vaccination of caregivers to protect infants. Despite proven benefit, maternal uptake of pertussis vaccine continues to remain suboptimal.

Areas Covered

Many studies have been conducted to address the suboptimal uptake of maternal pertussis vaccination. This systematic review was undertaken to systematically identify those studies, highlight the most successful strategies and find the knowledge gaps that need to be filled over the coming years to improve vaccine uptake. Twenty-five studies were identified from six different databases.

Expert opinion

Five different interventions were shown to be successful in promoting uptake of pertussis vaccination: (1) standing orders, (2) opt-in orders, (3) provider education, (4) on-site vaccination and (5) interactive patient education. Three major knowledge gaps were also identified that need to be filled over the coming years: (1) lack of studies in low- and middle-income countries, (2) lack of studies targeting midwives and/or home birth and (3) lack of studies on the process of vaccine communication.

中文翻译：

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增加孕产妇百日咳疫苗接种率的策略

 抽象的

 介绍

百日咳是一种高度传染性呼吸道疾病，导致尚未接种白喉-破伤风-百日咳原发疫苗系列的婴儿发病率和死亡率不成比例。在过去的几十年中，许多国家开始对孕妇进行产前疫苗接种或对护理人员进行产后疫苗接种以保护婴儿。尽管已证明有好处，但母亲对百日咳疫苗的吸收仍然不够理想。

 涵盖领域

已经开展了许多研究来解决孕产妇百日咳疫苗接种效果不佳的问题。进行这次系统审查的目的是系统地识别这些研究，突出最成功的策略，并找到未来几年需要填补的知识空白，以提高疫苗的使用率。从六个不同的数据库中确定了二十五项研究。

 专家意见

五种不同的干预措施被证明可以成功促进百日咳疫苗接种：（1）常规订单，（2）选择加入订单，（3）提供者教育，（4）现场疫苗接种和（5）互动患者教育。还确定了未来几年需要填补的三个主要知识差距：(1) 缺乏低收入和中等收入国家的研究，(2) 缺乏针对助产士和/或家庭分娩的研究，(3) 缺乏针对助产士和/或家庭分娩的研究疫苗传播过程的研究。