Abstract

Marla Sokolowski is a true pioneer in behavioral genetics, having made the first molecular delineation of a naturally occurring behavioral polymorphism in her work on the foraging locus in Drosophila melanogaster. The gene was subsequently found to be responsible for behavioral variants and types in many other species, both invertebrate and mammal (human). The path to get there is a paradigmatic example of how to use the power of genetic analysis, including some rather esoteric techniques, to zero in on a gene and delineate its molecular identity and its pleiotropic roles.

中文翻译：

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从 Marla Sokolowski 那里学习数量遗传学

摘要

Marla Sokolowski 是行为遗传学的真正先驱，在她对黑腹果蝇觅食位点的研究中首次对自然发生的行为多态性进行了分子描述。随后发现该基因与许多其他物种的行为变异和类型有关，包括无脊椎动物和哺乳动物（人类）。到达那里的途径是一个典型的例子，说明如何使用基因分析的力量，包括一些相当深奥的技术，将基因归零并描绘其分子身份和多效性作用。