A recent article by Lilascharoen et al. identified two distinct pathways in the globus pallidus (GPe) that are associated with discrete behaviors. Dysfunctions in these pathways were shown to underlie Parkinsonian motor and cognitive deficits in mice, and selective manipulation of these circuits rescued locomotor deficits and improved behavioral flexibility.

中文翻译：

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独特的苍白球回路调节运动和认知功能

Lilascharoen等人最近发表的一篇文章。确定了苍白球（GPe）中与离散行为相关的两条不同通路。这些通路的功能障碍被证明是小鼠帕金森病运动和认知缺陷的基础，选择性操纵这些通路可以挽救运动缺陷并改善行为灵活性。