The mechanical integrity of rolled ZM21 Mg was improved by equal channel angular pressing (ECAP) to function as a potential biodegradable bone screw implant. Electron backscattered diffraction (EBSD) revealed deformed grains of 45 µm observed in rolled ZM21 Mg. They were transformed to equiaxed fine grains of 5.4 µm after 4^th pass ECAP. The yield strength of rolled and ECAPed ZM21 Mg alloys were comparable. In contrast, 4^th pass ZM21 Mg exhibited relatively higher elongation when compared to rolled sample. The mechanical properties of rolled and ECAPed ZM21 Mg were dependant on both grain refinement and crystallographic texture. The rolled and 4^th pass ECAPed tensile samples exhibited nonlinear deterioration of mechanical properties when tested after 7, 14, 21 and 28 days immersion in Hank’s solution. The evaluation signifies that regardless their processing condition, ZM21 Mg alloys are suitable for surgical areas that requires high mechanical strength. In addition, the 4^th pass ECAP samples were viable to MG-63 cells proving themselves to be promising candidates for future in vivo studies.

通过等通道角挤压 (ECAP) 提高轧制 ZM21 Mg 的机械完整性，以用作潜在的可生物降解骨螺钉植入物。电子背散射衍射 (EBSD) 显示在轧制的 ZM21 Mg 中观察到 45 µm 的变形晶粒。在^第4^次ECAP后，它们转变为 5.4 µm 的等轴细晶粒。轧制和 ECAPed ZM21 镁合金的屈服强度相当。相比之下，与轧制样品相比，^第4 道^次ZM21 Mg 表现出相对较高的延伸率。轧制和 ECAPed ZM21 Mg 的机械性能取决于晶粒细化和结晶织构。轧制和^第4在汉克溶液中浸泡 7、14、21 和 28 天后测试时，通过 ECAPed 的拉伸样品表现出机械性能的非线性劣化。评估表明，无论加工条件如何，ZM21 镁合金都适用于需要高机械强度的手术区域。此外，第 4^次ECAP 样品对 MG-63 细胞是可行的，这证明它们是未来体内研究的有希望的候选物。