The effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension in vivo were determined. Feeding with supplemented diet with pulp reduced heart rate, mean arterial pressure, systolic and diastolic blood pressure levels of hypertensive-treated groups. Moreover, hypertensive-treated groups fed with fruit pulp supplemented diets had significantly (p < 0.05) lower level of serum pro-inflammatory markers when compared to untreated hypertensive group. Furthermore, feeding with supplemented diet with pulp and captopril administration reduced AChE, BChE, ACE, and arginase activities of hypertensive-treated groups. The fruit pulp supplemented diet also increased antioxidant status of hypertensive-treated groups. This was supported by the histopathological examination of the kidney and heart tissues. These beneficial effects could in part be the explanations of ethnomedicinal uses of the fruit pulp in the management of hypertension. Nevertheless, the higher percentage inclusion of the pulp showed higher antihypertensive effects.

确定了Chrysophyllum albidum果肉对血液动力学参数、促炎标志物、抗氧化参数和与体内高血压相关的关键生物分子的影响。用含有果肉的补充饮食喂养降低了高血压治疗组的心率、平均动脉压、收缩压和舒张压水平。此外，喂食补充果肉的饮食的高血压治疗组有显着（p < 0.05) 与未治疗的高血压组相比，血清促炎标志物水平较低。此外，补充饮食并给予果肉和卡托普利可降低高血压治疗组的 AChE、BChE、ACE 和精氨酸酶活性。补充果肉的饮食也增加了高血压治疗组的抗氧化状态。这得到了肾脏和心脏组织的组织病理学检查的支持。这些有益作用可能部分是对果肉在高血压管理中的民族医学用途的解释。尽管如此，纸浆的含量越高，显示出的抗高血压效果越好。