Objectives Accelerated atherosclerosis is a well-established phenomenon after coronary artery bypass grafting surgery (CABG). In this study, we analysed coronary artery calcium (CCS) progression after CABG. Methods We retrospectively measured the CCS Agatston score (AS), volume score (VS) and mass score (MS) of 39 patients before and after CABG. The annualised CCS change and annualised CCS percent change of each coronary artery, coronary artery segments proximal and distal to anastomosis were analysed. Results Mean age at the time of the surgery was 59.8±8.5 years. Follow-up period between the first and second CT scans was 6.7±2.8 (range, 1.1–12.8) years. Annualised CCS percent change (AS, VS and MS) of the coronary segments proximal-to-anastomosis did not differ from that of the non-grafted coronary arteries as follow: segments proximal-to-anastomosis: median (Q1–Q3) 12.8 (5.0–37.4), 13.7 (6.1–41.1) and 14.9 (5.4–53.7), left main coronary artery 12.6 (7.4–43.8), 22.0 (8.1–44.4) and 18.2 (7.3–57.4), non-grafted left circumflex artery: 13.5 (4.4–38.1), 10.5 (2.9–45.2) and 11.5 (7.1–47.9) and non-grafted right coronary artery: 31.4 (14.4–74.5), 25.2 (16.7–62.0) and 31.3 (23.8–85.6), respectively. Likewise, annualised percent change (AS, VS and MS) was similar between the native coronary arteries. Multivariate regression analysis showed that diabetes mellitus was the only predictor of annualised percent progression of the total CCS of >15% (HR, 8.12; 95% CI, 1.05 to 26.6; p=0.04). Conclusion The CCS post-CABG did not follow an accelerated progression process. Among coronary artery disease risk factors, diabetes mellitus is the only predictor of annualised CCS percent progression of >15% post-CABG. Data are available upon reasonable request.

中文翻译：

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冠状动脉旁路移植术后冠状动脉钙化进展

目的 加速动脉粥样硬化是冠状动脉旁路移植手术 (CABG) 后公认的现象。在这项研究中，我们分析了 CABG 后冠状动脉钙化 (CCS) 的进展。方法回顾性测量39例CABG前后CCS Agatston评分（AS）、体积评分（VS）和质量评分（MS）。分析了每个冠状动脉的年化 CCS 变化和年化 CCS 百分比变化，冠状动脉段近端和远端吻合。结果 手术时的平均年龄为 59.8±8.5 岁。第一次和第二次 CT 扫描之间的随访时间为 6.7±2.8（范围，1.1-12.8）年。吻合口近端冠状动脉节段的年化 CCS 百分比变化（AS、VS 和 MS）与未移植冠状动脉的年化百分比变化（AS、VS 和 MS）如下：近端吻合段：中位 (Q1–Q3) 12.8 (5.0–37.4)、13.7 (6.1–41.1) 和 14.9 (5.4–53.7)，左冠状动脉主干 12.6 (7.4–43.8)、22.0 (8.1–44.4) ) 和 18.2 (7.3-57.4)，未移植的左回旋支：13.5 (4.4-38.1)、10.5 (2.9-45.2) 和 11.5 (7.1-47.9) 和未移植的右冠状动脉：31.4 (14.5.4)- ，分别为 25.2 (16.7–62.0) 和 31.3 (23.8–85.6)。同样，天然冠状动脉之间的年化百分比变化（AS、VS 和 MS）相似。多变量回归分析显示，糖尿病是总 CCS 年化百分比进展 >15% 的唯一预测因素（HR，8.12；95% CI，1.05 至 26.6；p=0.04）。结论 CABG 后 CCS 并未遵循加速进展过程。在冠心病危险因素中，糖尿病是 CABG 后年化 CCS 进展百分比 >15% 的唯一预测因素。可应合理要求提供数据。