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My life with the Red Queen in fishery genetics
ICES Journal of Marine Science ( IF 3.1 ) Pub Date : 2021-05-19 , DOI: 10.1093/icesjms/fsab112
W Stewart Grant 1
Affiliation  

I had the privilege of being a part of fishery genetics from its start in the 1970s, when protein electrophoresis was first used to identify stocks of commercially important fishes and shellfishes. Research questions in fishery genetics have evolved tremendously over the past few decades, as new molecular techniques changed the nature of the questions that could be posed. The development of new DNA methods spurred the development of new theoretical models, new statistical methods and an unending stream of computer programs. These developments have led to conceptual shifts in the understanding of natural populations and how to manage them. Twists and turns in the history of fishery genetics parallel the story of the Red Queen in Lewis Carroll's Through the Looking Glass. I have had to “run in place” during my career to learn new techniques and ideas that, in turn, have been replaced with yet newer ones. However, my personal challenge throughout my career has been to develop “scientific intuition” to find underlying causes in datasets. Even though we now have the ability to sequence entire genomes, it is premature to announce the “end of history” for technical and conceptual advances in fishery genetics.

中文翻译:

我在渔业遗传学中与红皇后的生活

从 1970 年代开始,我就有幸成为渔业遗传学的一部分,当时蛋白质电泳首次用于鉴定具有商业重要性的鱼类和贝类的种群。在过去的几十年里,渔业遗传学的研究问题发生了巨大的变化,因为新的分子技术改变了可能提出的问题的性质。新 DNA 方法的发展促进了新理论模型、新统计方法和源源不断的计算机程序的发展。这些发展导致了对自然种群以及如何管理它们的理解的概念转变。渔业遗传学历史上的曲折与刘易斯卡罗尔的《镜花水月》中红皇后的故事相似。在我的职业生涯中,我不得不“原地踏步”来学习新技术和新想法,而这些新技术和想法又被更新的技术和想法所取代。然而,在我的整个职业生涯中,我个人面临的挑战是培养“科学直觉”来找到数据集中的根本原因。尽管我们现在有能力对整个基因组进行测序,但现在宣布渔业遗传学技术和概念进步的“历史终结”还为时过早。
更新日期:2021-05-19
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