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Dielectrophoresis velocities response on tapered electrode profile: simulation and experimental
Microelectronics International ( IF 0.7 ) Pub Date : 2019-04-01 , DOI: 10.1108/mi-06-2018-0037
Muhammad Izzuddin Abd Samad , Muhamad Ramdzan Buyong , Shyong Siow Kim , Burhanuddin Yeop Majlis

The purpose of this paper is to use a particle velocity measurement technique on a tapered microelectrode device via changes of an applied voltage, which is an enhancement of the electric field density in influencing the dipole moment particles. Polystyrene microbeads (PM) have used to determine the responses of the dielectrophoresis (DEP) voltage based on the particle velocity technique.,Analytical modelling was used to simulate the particles’ polarization and their velocity based on the Clausius–Mossotti Factor (CMF) equation. The electric field intensity and DEP forces were simulated through the COMSOL numerical study of the variation of applied voltages such as 5 V p-p, 7 V p-p and 10 V p-p. Experimentally, the particle velocity on a tapered DEP response was quantified via the particle travelling distance over a time interval through a high-speed camera adapted to a high-precision non-contact depth measuring microscope.,The result of the particle velocity was found to increase, and the applied voltage has enhanced the particle trajectory on the tapered microelectrode, which confirmed its dependency on the electric field intensity at the top and bottom edges of the electrode. A higher magnitude of particle levitation was recorded with the highest particle velocity of 11.19 ± 4.43 µm/s at 1 MHz on 10 V p-p, compared to the lowest particle velocity with 0.62 ± 0.11 µm/s at 10 kHz on 7 V p-p.,This research can be applied for high throughout sensitivity and selectivity of particle manipulation in isolating and concentrating biological fluid for biomedical implications.,The comprehensive manipulation method based on the changes of the electrical potential of the tapered electrode was able to quantify the magnitude of the particle trajectory in accordance with the strong electric field density.

中文翻译:

锥形电极剖面上的介电泳速度响应:模拟和实验

本文的目的是通过改变外加电压在锥形微电极装置上使用粒子速度测量技术,这是在影响偶极矩粒子时增强电场密度。聚苯乙烯微珠 (PM) 已用于基于粒子速度技术确定介电泳 (DEP) 电压的响应。,基于克劳修斯-莫索蒂因子 (CMF) 方程,使用解析建模来模拟粒子的极化及其速度. 电场强度和 DEP 力通过 COMSOL 数值研究对 5 V pp、7 V pp 和 10 V pp 等施加电压的变化进行模拟。实验上,通过适用于高精度非接触式深度测量显微镜的高速相机,通过粒子在一段时间间隔内的行进距离量化锥形 DEP 响应上的粒子速度。发现粒子速度的结果增加,施加的电压增强了锥形微电极上的粒子轨迹,这证实了它对电极顶部和底部边缘电场强度的依赖性。与在 7 V pp 上 10 kHz 下的 0.62 ± 0.11 µm/s 的最低粒子速度相比,在 10 V pp 上以 1 MHz 的最高粒子速度记录到更高的粒子悬浮量。
更新日期:2019-04-01
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