Entangled Porous Titanium Alloy Metal Rubber (EPTA-MR) was used as a nucleus pulposus material in the design of non-fusion intervertebral disc prosthesis for the first time. A novel artificial lumbar intervertebral disc prosthesis was designed by reconstructing the lumbar model with reverse engineering technology, and the biomechanical behavior of the prosthesis was simulated under varied working conditions. The nucleus pulposus size was determined by the actual size of human prosthesis. EPTA-MR samples with different densities were prepared by medical titanium alloy wire experimental studies were conducted on static stiffness, damping energy consumption, and fatigue life. The results indicated that the static stiffness of EPTA-MR could reach approximately 1500 N·mm⁻¹, and its loss factor remained higher than 0.2, and the variation range was relatively small, with excellent vibration damping capacity and bearing capacity. Among them, the overall performance of EPTA-MR with a density of 2.5 g·cm⁻³ was closer to that of the physiologic intervertebral disc. A macro experiment of five million fatigue vibration tests combined with microstructure observation exhibited a wear rate of only 0.9396 g·MC⁻¹, with no noticeable change in the internal micro-morphology. Therefore, the EPTA-MR has a broad application prospect as the nucleus pulposus material of artificial intervertebral disc prosthesis.

缠结多孔钛合金金属橡胶（EPTA-MR）首次被用作非融合椎间盘假体设计中的髓核材料。采用逆向工程技术重建腰椎模型，设计了一种新型人工腰椎间盘假体，模拟了假体在不同工作条件下的生物力学行为。髓核大小由人体假体的实际大小决定。制备不同密度的EPTA-MR样品，对医用钛合金丝进行静刚度、阻尼能耗和疲劳寿命实验研究。结果表明，EPTA-MR 的静刚度可以达到约 1500 N·mm ^-1，其损耗因子保持在0.2以上，变化幅度较小，具有优良的减振能力和承载能力。其中，密度为2.5 g·cm ^-3的EPTA-MR的综合性能更接近生理性椎间盘。500万次疲劳振动试验结合微观组织观察的宏观实验表明，磨损率仅为0.9396 g·MC ^-1，内部微观形貌没有明显变化。因此，EPTA-MR作为人工椎间盘假体的髓核材料具有广阔的应用前景。