Co-endemicity of SARS-CoV-2 and dengue virus (DV) infection is becoming a matter of serious concern as it has been already reported that antibodies (Ab) elicited by SARS-CoV-2 infection can produce false-positive results in dengue IgG and IgM rapid tests and vice versa. Here we communicate that five of thirteen DV antibody-positive serum samples from Kolkata, archived in 2017 (predating the COVID-19 outbreak), produced false-positive results in SARS-CoV-2 IgG/IgM lateral flow-based rapid tests. Our results emphasize the importance of implementing tests with higher specificity to conduct sero-surveillance for accurate estimation of SARS-CoV-2/DV prevalence in regions where both viruses now co-exist.

中文翻译：

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存档的登革热血清样本在基于 SARS-CoV-2 横向流动的快速抗体测试中产生假阳性结果

SARS-CoV-2 和登革热病毒 (DV) 感染的共同流行正成为一个严重关注的问题，因为已有报道称，由 SARS-CoV-2 感染引起的抗体 (Ab) 会在登革热中产生假阳性结果IgG 和 IgM 快速检测，反之亦然。在这里，我们传达了 2017 年存档的来自加尔各答的 13 个 DV 抗体阳性血清样本中的五个（在 COVID-19 爆发之前），在基于 SARS-CoV-2 IgG/IgM 的侧流快速检测中产生了假阳性结果。我们的结果强调了实施具有更高特异性的测试以进行血清监测以准确估计两种病毒现在共存地区的 SARS-CoV-2/DV 流行率的重要性。