The conjunctiva is the largest component of the ocular surface. It can be damaged by various pathological processes leading to scarring, loss of tissue and dysfunction. Depending on the amount of damage, restoration of function may require a conjunctival graft. Numerous studies have investigated biological and synthetic substrates in the search for optimal conditions for the ex vivo culture of conjunctival epithelial cells that can be used as tissue grafts for transplantation. These substrates have advantages and disadvantages that are specific to the characteristics of each material; the development of an improved material remains a priority. This review is the second of a two-part review in The Ocular Surface. In the first review, the structure and function of the conjunctiva was evaluated with a focus on the extracellular matrix and the basement membrane, and biological and mechanical characteristics of the ideal substrate with recommendations for further studies. In this review the types of biological and synthetic substrates used for conjunctival transplantation are discussed including substrates based on the extracellular matrix. .

结膜是眼表的最大组成部分。它可以被导致疤痕、组织损失和功能障碍的各种病理过程损坏。根据损伤的程度，功能的恢复可能需要结膜移植。许多研究调查了生物和合成底物，以寻找离体的最佳条件结膜上皮细胞的培养物，可用作移植的组织移植物。这些基材各有优缺点，具体取决于每种材料的特性；改进材料的开发仍然是一个优先事项。这篇评论是 The Ocular Surface 两篇评论中的第二篇。在第一次审查中，对结膜的结构和功能进行了评估，重点是细胞外基质和基底膜，以及理想基质的生物学和机械特性，并提出了进一步研究的建议。在这篇综述中，讨论了用于结膜移植的生物和合成底物的类型，包括基于细胞外基质的底物。.