Recently, dental resin adhesives are being incorporated with several nanoparticles to improve their mechanical and biological features. This study aimed to synthesize and characterize silanized graphene oxide (SGO) nanoparticles and assess the spectral, microbiological, and mechanical analysis of SGO-modified adhesive bonded to orthodontic brackets. Graphene oxide, manufactured using Hummer's method, was silanized utilizing tetraethylorthosilicate to synthesize SGO nanoparticles. The adhesive's characterization along with their biological and physical characteristics were assessed using scanning electron microscopy and energy dispersive X-ray spectroscopy; its degree of conversion (DC), cytotoxicity, antibacterial effect, shear bond strength (SBS), and adhesive remnant index (ARI) were examined. Transbond XT (control adhesive) was modified by incorporating 0.25 wt% and 0.5 wt% SGO-modified adhesive, which served as the experimental groups. Sixty orthodontic brackets were bonded to tooth surfaces for each study group (n = 20). Five disks of control and experimental groups were prepared measuring 5 mm in diameter and 1 mm in height each. SGO nanoparticles were synthesized with 100–700 nm in size and 1–2 nm thickness. Among the experimental groups, the samples treated with 0.25 wt% SGO-modified adhesive showed the lowest mean DC score (38.46 ± 5.12), the highest mean SBS values (13.84 ± 2.55 MPa), and the least ARI (post-thermocycling) scores (1.33 ± 0.54). 0.25 wt% SGO-modified adhesive samples showed a greater relative biofilm viability against S. mutans than 0.5 wt% SGO-modified adhesive samples after 24 h and 30 days. 0.25 wt% SGO-modified adhesive group showed higher SBS, sufficient durability, greatest bactericidal and least cytotoxic effect than 0.5 wt% SGO-modified adhesive and Transbond XT.

最近，牙科树脂粘合剂正与几种纳米颗粒结合以改善其机械和生物特性。本研究旨在合成和表征硅烷化氧化石墨烯 (SGO) 纳米粒子，并评估粘合在正畸托槽上的 SGO 改性粘合剂的光谱、微生物学和力学分析。使用 Hummer 方法制造的氧化石墨烯使用原硅酸四乙酯进行硅烷化以合成 SGO 纳米颗粒。使用扫描电子显微镜和能量色散 X 射线光谱评估粘合剂的特性及其生物和物理特性；对其转化程度（DC）、细胞毒性、抗菌作用、剪切粘合强度（SBS）和残胶指数（ARI）进行了检测。 wt%和 0.5  wt% SGO 改性粘合剂，作为实验组。每个研究组 (n = 20) 将 60 个正畸托槽粘合到牙齿表面。准备了五个控制组和实验组的圆盘，每个圆盘的直径为 5 毫米，高度为 1 毫米。合成的 SGO 纳米颗粒大小为 100-700 nm，厚度为 1-2 nm。在实验组中，用 0.25 wt% SGO 改性粘合剂处理的样品 表现出最低的平均 DC 评分（38.46 ± 5.12）、最高的平均 SBS 值（13.84 ± 2.55 MPa）和最低的 ARI（热循环后）评分(1.33±0.54)。0.25  wt% SGO 改性的粘合剂样品显示出比 0.5 更大的针对变形链球菌的相对生物膜活力24 小时和 30 天后的重量百分比SGO 改性粘合剂样品。与 0.5 wt% SGO 改性粘合剂和 Transbond XT相比，0.25  wt% SGO 改性粘合剂组显示出更高的 SBS、足够的耐久性、最大的杀菌和最小的细胞毒性作用 。