Pyrite bio-oxidation can improve the gold leaching extent of refractory gold ores, but it can also cause environmental pollution. In this work, common gangue minerals (feldspar, mica, and quartz) were studied to analyze their solubilization under industrial bio-oxidation condition and their effects on pyrite bio-oxidation. The results show that: They all have certain solubilization under bio-oxidation conditions, and the solubilization sequence is in the reduction order of feldspar, mica, quartz. They all inhibit the pyrite bio-oxidation process, and the order of inhibition is mica, quartz, and feldspar. Reasons for the inhibition include ion toxicity, pulp oppresses, passivation, and changes in microbial communities. The results of response surface analysis indicated that the interaction between feldspar and quartz was the most significant, followed by feldspar and mica, while the interaction between mica and quartz was not obvious. When the weight ratio of pyrite, feldspar, mica and quartz is 10:4:5:11, pyrite dissolves the least, while the weight ratio is 5:9:1:15, pyrite dissolves the most easily. The results provide a reference for related research and provide theoretical support and process optimization guidance for environmental protection and industrial bio-oxidation process.

黄铁矿生物氧化可以提高难选金矿石的浸金程度，但也会造成环境污染。在这项工作中，研究了常见的脉石矿物（长石、云母和石英），分析了它们在工业生物氧化条件下的增溶作用及其对黄铁矿生物氧化的影响。结果表明：它们在生物氧化条件下都有一定的增溶作用，增溶顺序为长石、云母、石英的还原顺序。它们都抑制黄铁矿生物氧化过程，抑制顺序为云母、石英、长石。抑制的原因包括离子毒性、纸浆压迫、钝化和微生物群落的变化。响应面分析结果表明，长石与石英之间的相互作用最为显着，其次是长石和云母，而云母和石英之间的相互作用不明显。当黄铁矿、长石、云母和石英的重量比为10：4：5：11时，黄铁矿溶解最少，而重量比为5：9：1：15时，黄铁矿最容易溶解。研究结果可为相关研究提供参考，为环保和工业生物氧化工艺提供理论支持和工艺优化指导。