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Distribution of nitric oxide in the rock cavy (Kerodon rupestris) brain II: The brainstem
Journal of Chemical Neuroanatomy ( IF 2.7 ) Pub Date : 2021-06-11 , DOI: 10.1016/j.jchemneu.2021.101989
Lucimário Thiago Félix de Araújo 1 , Maria Emanuela Martins Dos Reis 1 , Wylqui Mikael Gomes de Andrade 1 , Nayra da Silva Resende 1 , Ruthnaldo Rodrigues Melo de Lima 1 , Expedito Silva do Nascimento 1 , Miriam Stela Maris de Oliveira Costa 1 , Judney Cley Cavalcante 1
Affiliation  

In a recent paper, we described the distribution of Nitric oxide (NO) in the diencephalon of the rock cavy (Kerodon rupestris). This present paper follows this work, showing the distribution of NO synthesizing neurons in the rock cavy's brainstem. For this, we used immunohistochemistry against the neuronal form of nitric oxide synthase (NOS) and NADPH diaphorase histochemistry. In contrast to the diencephalon in the rock cavy, where the NOS neurons were seen to be limited to some nuclei in the thalamus and hypothalamus, the distribution of NOS in the brainstem is widespread. Neurons immunoreactive to NOS (NOS-ir) were seen as rostral as the precommissural nuclei and as caudal as the caudal and gelatinous parts of the spinal trigeminal nucleus. Places such as the raphe nuclei, trigeminal complex, superior and inferior colliculus, oculomotor complex, periaqueductal grey matter, solitary tract nucleus, laterodorsal tegmental nucleus, pedunculopontine tegmental, and other nuclei of the reticular formation are among the locations with the most NOS-ir neurons. This distribution is similar, but with some differences, to those described for other rodents, indicating that NO also has an important role in rock cavy's physiology.



中文翻译:

石豚 (Kerodon rupestris) 大脑中一氧化氮的分布 II:脑干

在最近的一篇论文中,我们描述了一氧化氮 (NO) 在岩豚间脑 ( Kerodon rupestris ) 中的分布。)。本文紧随这项工作,展示了石豚鼠脑干中 NO 合成神经元的分布。为此,我们使用了针对神经元形式的一氧化氮合酶 (NOS) 和 NADPH 心肌黄酶组织化学的免疫组织化学。与岩豚中的间脑相比,NOS 神经元被认为仅限于丘脑和下丘脑中的某些细胞核,而 NOS 在脑干中的分布是广泛的。对 NOS (NOS-ir) 具有免疫反应性的神经元被视为与前连合核一样位于喙侧,与脊髓三叉神经核的尾部和凝胶状部分一样位于尾部。中缝核、三叉神经复合体、上下丘、动眼神经复合体、导水管周围灰质、孤束核、背侧被盖核、脚桥被盖、网状结构的其他细胞核是 NOS-ir 神经元最多的位置之一。这种分布与其他啮齿动物的分布相似,但有一些差异,这表明 NO 在岩豚的生理学中也有重要作用。

更新日期:2021-06-19
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