Optical biosensors show attractive performance in medical sensing in the event of using different nanoparticles in their design. Owing to their unique optical characteristics and biological compatibility, gold nanoparticles (GNPs), silver nanoparticles (AgNPs), bimetallic nanoparticles and magnetic nanoparticles have been broadly implemented in making sensing tools. The functionalization of these nanoparticles with different components provides an excellent opportunity to assemble selective and sensitive sensing materials to detect various biological molecules related to breast cancer. This review summarizes the recent application of optical biosensing devices based on nanomaterials and discusses their pros and cons to improve breast cancer detection in real samples. In particular, the main constituent elements of these optical biosensors including recognition and transducer elements, types of applied nanostructures, analytical sensing procedures, sensor detection ranges and limit of detection (LOD), are expressed in detail.

如果在其设计中使用不同的纳米粒子，光学生物传感器在医学传感方面显示出有吸引力的性能。由于其独特的光学特性和生物相容性，金纳米粒子 (GNP)、银纳米粒子 (AgNP)、双金属纳米粒子和磁性纳米粒子已广泛应用于制造传感工具。这些具有不同成分的纳米颗粒的功能化为组装选择性和灵敏的传感材料以检测与乳腺癌相关的各种生物分子提供了极好的机会。本综述总结了基于纳米材料的光学生物传感设备的最新应用，并讨论了它们在改善实际样本中乳腺癌检测方面的利弊。特别是，