Physical activity is of prime importance in non-pharmacological Parkinson’s disease (PD) treatment. The current study examines the effectiveness and feasibility of sport climbing in PD patients in a single-centre, randomised controlled, semi-blind trial. A total of 48 PD patients without experience in climbing (average age 64 ± 8 years, Hoehn & Yahr stage 2–3) were assigned either to participate in a 12-week sport climbing course (SC) or to attend an unsupervised physical training group (UT). The primary outcome was the improvement of symptoms on the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale part III (MDS-UPDRS-III). Sport climbing was associated with a significant reduction of the MDS-UPDRS-III (−12.9 points; 95% CI −15.9 to −9.8), while no significant improvement was to be found in the UT (−3.0 points; 95% CI −6.0 to 0.1). Bradykinesia, rigidity and tremor subscales significantly improved in SC, but not in the unsupervised control group. In terms of feasibility, the study showed a 99% adherence of participants to climbing sessions and a drop-out rate of only 8%. No adverse events occurred. This trial provides class III evidence that sport climbing is highly effective and feasible in mildly to moderately affected PD patients.

身体活动在非药物帕金森病 (PD) 治疗中至关重要。目前的研究在单中心、随机对照、半盲试验中检查了运动攀登在 PD 患者中的有效性和可行性。共有 48 名没有攀岩经验的 PD 患者（平均年龄 64 ± 8 岁，Hoehn & Yahr 2-3 期）被分配参加为期 12 周的运动攀岩课程 (SC) 或参加无人监督的体能训练组(UT)。主要结果是运动障碍协会赞助修订的统一帕金森病评定量表第 III 部分 (MDS-UPDRS-III) 的症状改善。运动攀登与 MDS-UPDRS-III 显着降低有关（-12.9 分；95% CI -15.9 至 -9.8），而在 UT 中没有发现显着改善（-3.0 分；95% CI -6.0 到 0.1）。运动迟缓、僵硬和震颤分量表在 SC 中显着改善，但在无人监督的对照组中没有显着改善。在可行性方面，该研究表明，参与者对攀岩课程的坚持率为 99%，辍学率仅为 8%。没有发生不良事件。该试验提供了 III 类证据，表明运动攀爬对轻度至中度受影响的 PD 患者非常有效和可行。