The respiratory-related evoked potential (RREP) is an established technique to study the neural processing of respiratory sensations. We examined the test-retest reliability of the RREP during an unloaded baseline condition (no dyspnea) and an inspiratory resistive loaded breathing condition (dyspnea) over a one-week period. RREPs were evoked by short inspiratory occlusions (150 ms) while EEG was continuously measured. The mean amplitudes of the RREP components Nf, P1, N1, P2, and P3 were studied. For the no dyspnea condition, moderate test-retest reliability for Nf (intraclass correlation coefficient ICC: 0.73) and P1 (ICC: 0.74), good test-retest reliability for N1 (ICC: 0.89) and P3 (ICC: 0.76), and excellent test-retest reliability for P2 (ICC: 0.92) was demonstrated. For the dyspnea condition, moderate test-retest reliability was found for Nf (ICC: 0.69) and P1 (ICC: 0.57) and good test-retest reliability for N1 (ICC: 0.77), P2 (ICC: 0.84), and P3 (ICC: 0.77). This indicates that the RREP components Nf, P1, N1, P2, and P3, elicited by inspiratory occlusions, show adequate reliability in a test-retest study design with or without parallel sustained resistive load-induced dyspnea.

呼吸相关诱发电位 (RREP) 是一种研究呼吸感觉神经处理的成熟技术。我们在一周内检查了 RREP 在无负荷基线条件（无呼吸困难）和吸气阻力负荷呼吸条件（呼吸困难）期间的重测可靠性。RREP 是由短暂的吸气闭塞 (150 ms) 引起的，同时连续测量 EEG。研究了 RREP 分量 Nf、P1、N1、P2 和 P3 的平均振幅。对于无呼吸困难情况，N​​f（组内相关系数ICC：0.73）和P1（ICC：0.74）的重测信度中等，N1（ICC：0.89）和P3（ICC：0.76）的重测信度良好，以及P2 的重测信度 (ICC: 0.92) 得到证明。对于呼吸困难的情况，Nf（ICC：0.69）和 P1（ICC：0.57）的重测信度中等，N1（ICC：0.77）、P2（ICC：0.84）和 P3（ICC：0.77）的重测信度良好。这表明由吸气阻塞引起的 RREP 成分 Nf、P1、N1、P2 和 P3，在测试-再测试研究设计中显示出足够的可靠性，有或没有平行的持续阻力性负载引起的呼吸困难。