Background: Supercritical fluid chromatography (SFC) is one of the powerful analytical techniques of modern times. Recently, extensive analytical work has been reported and is in progress by utilizing the advanced features of SFC. Low solvent consumption, high sensitivity, and solvent recovery make it advantageous over the traditional liquid chromatographic techniques. It utilizes supercritical fluids having properties of both liquid and gases, making the applicability of this technique possible for a wider range of analytes.

Methods: Various research reports were collected from search engines like Sciencedirect, Pubmed, Researchgate, and Google Scholar. Further, upon a thorough study of these reports, significant findings/data was collected and compiled under suitable headings. Important parameters/ conditions utilized in methodologies are depicted with the help of tables in this study.

Results: It was found in various reports that SFC and its hyphenation with mass spectroscopy (MS), ultraviolet spectroscopy (UV), high-resolution mass spectrometry (HRMS), photodiode array detector (PDA), nuclear magnetic resonance (NMR), charged aerosol detector (CAD), etc., have made possible to quantify analytes even in ultra-small concentrations in complex matrices. These techniques have been successfully employed for the quantification of a wide variety of analytes with excellent accuracy, selectivity, and sensitivity.

Conclusion: The present review highlights the recent applications of SFC techniques in various analytical fields, such as pesticide analysis, vitamin analysis, enantioseparation, lipid analysis, drug metabolite estimation, polycyclic aromatic hydrocarbons, and steroid analysis. Reports from 2017 to 2020 have been included in this compilation.

背景：超临界流体色谱 (SFC) 是现代强大的分析技术之一。最近，广泛的分析工作已被报道并正在利用 SFC 的高级功能进行。低溶剂消耗、高灵敏度和溶剂回收率使其优于传统的液相色谱技术。它利用具有液体和气体特性的超临界流体，使该技术适用于更广泛的分析物。

方法：从 Sciencedirect、Pubmed、Researchgate 和 Google Scholar 等搜索引擎收集了各种研究报告。此外，在对这些报告进行彻底研究后，收集了重要的发现/数据并在适当的标题下进行了汇编。在本研究中的表格的帮助下描述了方法学中使用的重要参数/条件。

结果：在各种报告中发现 SFC 及其与质谱 (MS)、紫外光谱 (UV)、高分辨率质谱 (HRMS)、光电二极管阵列检测器 (PDA)、核磁共振 (NMR)、带电气溶胶检测器 (CAD) 等使即使在复杂基质中的超小浓度分析物也能定量。这些技术已成功用于多种分析物的定量分析，具有出色的准确度、选择性和灵敏度。

结论：本综述重点介绍了 SFC 技术在各种分析领域的最新应用，如农药分析、维生素分析、对映分离、脂质分析、药物代谢物估计、多环芳烃和类固醇分析。2017 年至 2020 年的报告已包含在本汇编中。