MicroRNA-488 inhibits neural inflammation and apoptosis in spinal cord injury through restraint on the HMGB1/TLR4/NF-κB signaling pathway.,Neuroreport

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MicroRNA-488 inhibits neural inflammation and apoptosis in spinal cord injury through restraint on the HMGB1/TLR4/NF-κB signaling pathway.
Neuroreport ( IF 1.6 ) Pub Date : 2021-06-07 , DOI: 10.1097/wnr.0000000000001680
Feng Niu ₁ , Shan Pan ₂

Affiliation

Secondary spinal cord injury (SCI), a reversible pathological change, involves neural inflammation and apoptosis. This study explored how microRNA (miR)-488, an inflammatory regulator as reported affected secondary SCI.

中文翻译：

MicroRNA-488 通过抑制 HMGB1/TLR4/NF-κB 信号通路抑制脊髓损伤中的神经炎症和细胞凋亡。

继发性脊髓损伤 (SCI) 是一种可逆的病理变化，涉及神经炎症和细胞凋亡。本研究探讨了 microRNA (miR)-488（一种据报道的炎症调节剂）如何影响继发性 SCI。

更新日期：2021-06-10

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