Transcription-coupled repair of DNA lesions takes place across all domains of life. A transcription-elongation factor, ELOF1, highly conserved in eukaryotes, has now been shown to play a key role in this process. Importantly, these findings also include evidence of a second transcription-coupled repair pathway in mammalian cells.

中文翻译：

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TCR 房间里的 ELOF(1) 蚂蚁

DNA 损伤的转录偶联修复发生在生命的各个领域。转录延伸因子 ELOF1 在真核生物中高度保守，现已证明在该过程中发挥关键作用。重要的是，这些发现还包括哺乳动物细胞中第二个转录偶联修复途径的证据。