In this work, the magnetic domains (MDs) orientation was evaluated from magnetite/maghemite nanoparticles (Fe₃O₄/γ-Fe₂O₃) NPs coated with Gadolinium (Gd³⁺) chelated with diethylenetriamine pentaacetate acid (Gd–DTPA). The (Fe₃O₄/γ–Fe₂O₃) superparamagnetic cores were configured by adding a DTPA organic layer and paramagnetic Gd as (Fe₃O₄/γ–Fe₂O₃)@Gd–DTPA NPs. The cores were obtained by coprecipitation and coated with additional modifications to the synthesis with Gd–DTPA. Analysis of properties showed that particles 9–12 nm, with Gd–DTPA layer thickness ∼10 nm increased their magnetisation from 62.72 to 75.82 emu/g. The result showed that the structure, particle size, composition, thickness and interface defects, as well as the anisotropy, play an important role in MDs orientation of (Fe₃O₄/γ–Fe₂O₃)@Gd–DTPA NPs. Magnetic force microscopy (MFM) analysis showed an MDs uniaxial orientation of 90 at magnetisation and disorder at zero conditions and demagnetisation. The MDs interactions showed uniaxial anisotropy defined in the direction of the magnetic field. These addressable and rotational features could be considered for potential applications to induce hydrogen proton alignment in water by longitudinal spin-lattice relaxation T ₁ and transversal spin-spin relaxation T ₂ as a dual contrast agent and as a theranostic trigger.

在这项工作中，磁畴 (MDs) 取向是从磁铁矿/磁赤铁矿纳米粒子 (Fe ₃ O ₄ / γ -Fe ₂ O ₃ ) NPs中评估的，这些纳米粒子涂有钆 (Gd ³⁺ )，与二亚乙基三胺五乙酸 (Gd-DTPA) 螯合. (Fe ₃ O ₄ / γ –Fe ₂ O ₃ ) 超顺磁核通过添加 DTPA 有机层和顺磁 Gd 作为 (Fe ₃ O ₄ / γ –Fe ₂ O ₃)@Gd–DTPA NP。核心是通过共沉淀获得的，并用 Gd-DTPA 对合成进行了额外的修改。性能分析表明，颗粒大小为 9-12 nm，Gd-DTPA 层厚度约为 10 nm，其磁化强度从 62.72 增加到 75.82 emu/g。结果表明，结构、粒径、成分、厚度和界面缺陷以及各向异性对 (Fe ₃ O ₄ / γ –Fe ₂ O ₃)@Gd–DTPA NP。磁力显微镜 (MFM) 分析显示 MDs 单轴取向在磁化和零条件和退磁下的无序状态下为 90。MDs 相互作用显示出在磁场方向上定义的单轴各向异性。这些可寻址和旋转特征可以考虑用于通过纵向自旋晶格弛豫T ₁和横向自旋自旋弛豫T ₂作为双重造影剂和治疗诊断触发在水中诱导氢质子排列的潜在应用。